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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04425COG: COG3151 Uncharacterized protein conserved in bacteria. (140 aa)    
Predicted Functional Partners:
CKO_04426
Hypothetical protein; KEGG: sec:SC3129 1.7e-95 yqiE; putative resistance protein K01515; COG: COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes; Psort location: Cytoplasmic, score:8.96.
  
    0.870
CKO_04423
Hypothetical protein; KEGG: aha:AHA_3762 4.3e-44 esterase YqiA; COG: COG3150 Predicted esterase.
 
     0.782
cpdA
Hypothetical protein; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes.
  
  
 0.772
parE
Hypothetical protein; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily.
       0.665
rsd
Hypothetical protein; Binds RpoD and negatively regulates RpoD-mediated transcription activation by preventing the interaction between the primary sigma factor RpoD with the catalytic core of the RNA polymerase and with promoter DNA. May be involved in replacement of the RNA polymerase sigma subunit from RpoD to RpoS during the transition from exponential growth to the stationary phase.
  
     0.657
CKO_00659
Hypothetical protein; COG: NOG06773 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.46.
  
     0.564
CKO_02304
COG: COG3637 Opacity protein and related surface antigens; Psort location: OuterMembrane, score:10.00.
  
     0.561
CKO_00152
Hypothetical protein; KEGG: azo:azo0595 6.1e-05 3',5'-cyclic-nucleotide phosphodiesterase K01120; COG: COG3159 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
     0.549
CKO_04502
Hypothetical protein; COG: NOG11454 non supervised orthologous group.
  
     0.543
CKO_04427
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
       0.538
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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