| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_03140 | CKO_04368 | CKO_03140 | CKO_04368 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | 0.532 |
| CKO_03140 | CKO_04614 | CKO_03140 | CKO_04614 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: sec:SC3266 0. arcB; aerobic respiration control sensor protein K07648; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.97. | 0.484 |
| CKO_03140 | CKO_04620 | CKO_03140 | CKO_04620 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96. | 0.973 |
| CKO_03140 | glnD | CKO_03140 | CKO_03202 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism. | 0.618 |
| CKO_03140 | glnE | CKO_03140 | CKO_04439 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.799 |
| CKO_03140 | ldh | CKO_03140 | CKO_01547 | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | Hypothetical protein; Catalyzes the conversion of lactate to pyruvate. | 0.417 |
| CKO_04368 | CKO_03140 | CKO_04368 | CKO_03140 | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | Hypothetical protein; KEGG: sdy:SDY_3873 1.3e-250 glnA; glutamine synthetase K01915; COG: COG0174 Glutamine synthetase; Psort location: Cytoplasmic, score:9.97. | 0.532 |
| CKO_04368 | CKO_04614 | CKO_04368 | CKO_04614 | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | Hypothetical protein; KEGG: sec:SC3266 0. arcB; aerobic respiration control sensor protein K07648; COG: COG0784 FOG: CheY-like receiver; Psort location: CytoplasmicMembrane, score:9.97. | 0.999 |
| CKO_04368 | CKO_04620 | CKO_04368 | CKO_04620 | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | Hypothetical protein; KEGG: sbo:SBO_3170 0. gltB; glutamate synthase, large subunit K00265; COG: COG0069 Glutamate synthase domain 2; Psort location: Cytoplasmic, score:8.96. | 0.590 |
| CKO_04368 | glnE | CKO_04368 | CKO_04439 | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.589 |
| CKO_04368 | ldh | CKO_04368 | CKO_01547 | Hypothetical protein; KEGG: sbo:SBO_2396 2.5e-190 evgS, evgA; putative sensor for regulator EvgA K07679; COG: COG0834 ABC-type amino acid transport/signal transduction systems, periplasmic component/domain; Psort location: CytoplasmicMembrane, score:9.82. | Hypothetical protein; Catalyzes the conversion of lactate to pyruvate. | 0.494 |
| CKO_04441 | CKO_04442 | CKO_04441 | CKO_04442 | Hypothetical protein. | Hypothetical protein; KEGG: aha:AHA_3770 5.9e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein. | 0.752 |
| CKO_04441 | CKO_04443 | CKO_04441 | CKO_04443 | Hypothetical protein. | COG: COG3103 SH3 domain protein. | 0.514 |
| CKO_04441 | glnE | CKO_04441 | CKO_04439 | Hypothetical protein. | Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.714 |
| CKO_04441 | hldE | CKO_04441 | CKO_04438 | Hypothetical protein. | Hypothetical protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.553 |
| CKO_04442 | CKO_04441 | CKO_04442 | CKO_04441 | Hypothetical protein; KEGG: aha:AHA_3770 5.9e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein. | Hypothetical protein. | 0.752 |
| CKO_04442 | CKO_04443 | CKO_04442 | CKO_04443 | Hypothetical protein; KEGG: aha:AHA_3770 5.9e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein. | COG: COG3103 SH3 domain protein. | 0.640 |
| CKO_04442 | glnE | CKO_04442 | CKO_04439 | Hypothetical protein; KEGG: aha:AHA_3770 5.9e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein. | Hypothetical protein; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB [...] | 0.770 |
| CKO_04442 | hldE | CKO_04442 | CKO_04438 | Hypothetical protein; KEGG: aha:AHA_3770 5.9e-40 adenylate cyclase K01768; COG: COG3025 Uncharacterized conserved protein. | Hypothetical protein; Catalyzes the phosphorylation of D-glycero-D-manno-heptose 7- phosphate at the C-1 position to selectively form D-glycero-beta-D- manno-heptose-1,7-bisphosphate; In the C-terminal section; belongs to the cytidylyltransferase family. | 0.629 |
| CKO_04443 | CKO_04441 | CKO_04443 | CKO_04441 | COG: COG3103 SH3 domain protein. | Hypothetical protein. | 0.514 |
