| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_04076 | CKO_04085 | CKO_04076 | CKO_04085 | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; COG: COG0409 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96; Belongs to the HypD family. | 0.705 |
| CKO_04076 | CKO_04384 | CKO_04076 | CKO_04384 | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. | 0.667 |
| CKO_04076 | CKO_04756 | CKO_04076 | CKO_04756 | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: stm:STM3455 1.3e-99 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775; COG: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; Psort location: Cytoplasmic, score:8.96. | 0.897 |
| CKO_04076 | ureG | CKO_04076 | CKO_04460 | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.943 |
| CKO_04085 | CKO_04076 | CKO_04085 | CKO_04076 | Hypothetical protein; COG: COG0409 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96; Belongs to the HypD family. | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | 0.705 |
| CKO_04085 | CKO_04384 | CKO_04085 | CKO_04384 | Hypothetical protein; COG: COG0409 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96; Belongs to the HypD family. | Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. | 0.994 |
| CKO_04085 | ureG | CKO_04085 | CKO_04460 | Hypothetical protein; COG: COG0409 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96; Belongs to the HypD family. | Hypothetical protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.862 |
| CKO_04384 | CKO_04076 | CKO_04384 | CKO_04076 | Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | 0.667 |
| CKO_04384 | CKO_04085 | CKO_04384 | CKO_04085 | Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; COG: COG0409 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96; Belongs to the HypD family. | 0.994 |
| CKO_04384 | ureG | CKO_04384 | CKO_04460 | Hypothetical protein; COG: COG0298 Hydrogenase maturation factor; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.867 |
| CKO_04756 | CKO_04076 | CKO_04756 | CKO_04076 | Hypothetical protein; KEGG: stm:STM3455 1.3e-99 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775; COG: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: eci:UTI89_C3084 0. hycE; formate hydrogenlyase subunit 5 precursor; COG: COG3261 Ni,Fe-hydrogenase III large subunit; Psort location: Cytoplasmic, score:8.96. | 0.897 |
| CKO_04756 | ureE | CKO_04756 | CKO_04458 | Hypothetical protein; KEGG: stm:STM3455 1.3e-99 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775; COG: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.401 |
| CKO_04756 | ureG | CKO_04756 | CKO_04460 | Hypothetical protein; KEGG: stm:STM3455 1.3e-99 slyD; FKBP-type peptidyl prolyl cis-trans isomerase (rotamase) K03775; COG: COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.846 |
| ureA | ureB | CKO_04455 | CKO_04456 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; KEGG: ece:Z1144 5.9e-40 ureB; putative urease structural subunit B (beta) K01429; COG: COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family. | 0.999 |
| ureA | ureC | CKO_04455 | CKO_04457 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; KEGG: ece:Z1584 1.5e-279 ureC_2; putative urease structural subunit C (alpha) K01428; COG: COG0804 Urea amidohydrolase (urease) alpha subunit; Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family. | 0.999 |
| ureA | ureD | CKO_04455 | CKO_04454 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.996 |
| ureA | ureE | CKO_04455 | CKO_04458 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly. Belongs to the UreE family. | 0.958 |
| ureA | ureF | CKO_04455 | CKO_04459 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; Required for maturation of urease via the functional incorporation of the urease nickel metallocenter. | 0.992 |
| ureA | ureG | CKO_04455 | CKO_04460 | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | Hypothetical protein; Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG. | 0.966 |
| ureB | ureA | CKO_04456 | CKO_04455 | Hypothetical protein; KEGG: ece:Z1144 5.9e-40 ureB; putative urease structural subunit B (beta) K01429; COG: COG0832 Urea amidohydrolase (urease) beta subunit; Belongs to the urease beta subunit family. | Hypothetical protein; KEGG: ece:Z1143 6.1e-45 ureA; putative urease structural subunit A (gamma) K01430; COG: COG0831 Urea amidohydrolase (urease) gamma subunit; Belongs to the urease gamma subunit family. | 0.999 |