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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
patAHypothetical protein; Catalyzes the aminotransferase reaction from putrescine to 2- oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. This is the first step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate (gamma-aminobutyrate or GABA) via 4- aminobutanal. Also functions as a cadaverine transaminase in a a L- lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate. (503 aa)    
Predicted Functional Partners:
speB
Hypothetical protein; Catalyzes the formation of putrescine from agmatine. Belongs to the arginase family. Agmatinase subfamily.
  
 0.942
speE
Hypothetical protein; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.
     
 0.920
argH
Hypothetical protein; KEGG: ssn:SSO_4133 2.5e-231 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score:8.96.
 
  
 0.916
patD
Hypothetical protein; Catalyzes the oxidation 4-aminobutanal (gamma- aminobutyraldehyde) to 4-aminobutanoate (gamma-aminobutyrate or GABA). This is the second step in one of two pathways for putrescine degradation, where putrescine is converted into 4-aminobutanoate via 4- aminobutanal. Also functions as a 5-aminopentanal dehydrogenase in a a L-lysine degradation pathway to succinate that proceeds via cadaverine, glutarate and L-2-hydroxyglutarate.
 
 0.914
CKO_03180
Hypothetical protein; KEGG: eco:b0186 0. ldcC; lysine decarboxylase 2, constitutive K01582; COG: COG1982 Arginine/lysine/ornithine decarboxylases.
   
 
 0.914
CKO_02469
Hypothetical protein; KEGG: ssn:SSO_0644 0. speF; ornithine decarboxylase isozyme, inducible K01581; COG: COG1982 Arginine/lysine/ornithine decarboxylases.
   
 
 0.911
argC
Hypothetical protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
 
  
 0.911
CKO_04340
Hypothetical protein; KEGG: stm:STM3114 0. speC; ornithine decarboxylase isozyme K01581; COG: COG1982 Arginine/lysine/ornithine decarboxylases.
   
 
 0.911
CKO_01578
Hypothetical protein; KEGG: sec:SC1519 1.5e-91 speG; spermidine N1-acetyltransferase K00657; COG: COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins; Psort location: Cytoplasmic, score:8.96.
   
 
 0.901
argA
Hypothetical protein; KEGG: ecj:JW2786 1.3e-211 argA; fused acetylglutamate kinase homolog (inactive) and amino acid N-acetyltransferase K00619; COG: COG0548 Acetylglutamate kinase; Psort location: Cytoplasmic, score:8.96; Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.896
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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