node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CKO_04489 | CKO_04490 | CKO_04489 | CKO_04490 | Hypothetical protein; COG: COG1451 Predicted metal-dependent hydrolase. | KEGG: ecp:ECP_3178 1.1e-148 hypothetical oxidoreductase YgjR; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score:8.96. | 0.622 |
CKO_04489 | rlmG | CKO_04489 | CKO_04488 | Hypothetical protein; COG: COG1451 Predicted metal-dependent hydrolase. | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.644 |
CKO_04490 | CKO_04489 | CKO_04490 | CKO_04489 | KEGG: ecp:ECP_3178 1.1e-148 hypothetical oxidoreductase YgjR; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; COG: COG1451 Predicted metal-dependent hydrolase. | 0.622 |
CKO_04490 | rlmG | CKO_04490 | CKO_04488 | KEGG: ecp:ECP_3178 1.1e-148 hypothetical oxidoreductase YgjR; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.540 |
nusG | rlmG | CKO_03008 | CKO_04488 | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.473 |
nusG | rplA | CKO_03008 | CKO_03006 | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | Hypothetical protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.925 |
nusG | rplL | CKO_03008 | CKO_03003 | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | Hypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.986 |
nusG | rpoB | CKO_03008 | CKO_03002 | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.991 |
nusG | trmD | CKO_03008 | CKO_03930 | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | Hypothetical protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.433 |
obg | rlmG | CKO_04587 | CKO_04488 | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.641 |
obg | rplA | CKO_04587 | CKO_03006 | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. | 0.869 |
obg | rplL | CKO_04587 | CKO_03003 | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. | 0.761 |
obg | rpoB | CKO_04587 | CKO_03002 | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.465 |
obg | trmD | CKO_04587 | CKO_03930 | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Hypothetical protein; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. | 0.708 |
rapA | rlmG | CKO_03323 | CKO_04488 | Hypothetical protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | 0.497 |
rapA | rpoB | CKO_03323 | CKO_03002 | Hypothetical protein; Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair; Belongs to the SNF2/RAD54 helicase family. RapA subfamily. | Hypothetical protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.983 |
rlmG | CKO_04489 | CKO_04488 | CKO_04489 | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Hypothetical protein; COG: COG1451 Predicted metal-dependent hydrolase. | 0.644 |
rlmG | CKO_04490 | CKO_04488 | CKO_04490 | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | KEGG: ecp:ECP_3178 1.1e-148 hypothetical oxidoreductase YgjR; COG: COG0673 Predicted dehydrogenases and related proteins; Psort location: Cytoplasmic, score:8.96. | 0.540 |
rlmG | nusG | CKO_04488 | CKO_03008 | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Hypothetical protein; Participates in transcription elongation, termination and antitermination. In the absence of Rho, increases the rate of transcription elongation by the RNA polymerase (RNAP), probably by partially suppressing pausing. In the presence of Rho, modulates most Rho-dependent termination events by interacting with the RNAP to render the complex more susceptible to the termination activity of Rho. May be required to overcome a kinetic limitation of Rho to function at certain terminators. Also involved in ribosomal RNA transcriptional antitermination; Belongs to the NusG [...] | 0.473 |
rlmG | obg | CKO_04488 | CKO_04587 | Hypothetical protein; Specifically methylates the guanine in position 1835 (m2G1835) of 23S rRNA. | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.641 |