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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tdcCHypothetical protein; Involved in the import of threonine and serine into the cell, with the concomitant import of a proton (symport system). Belongs to the amino acid/polyamine transporter 2 family. SdaC/TdcC subfamily. (443 aa)    
Predicted Functional Partners:
CKO_04517
Hypothetical protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
  
 0.784
tdcD
Hypothetical protein; Catalyzes the conversion of propionyl phosphate and ADP to propionate and ATP.
  
  
 0.594
CKO_04514
Hypothetical protein; KEGG: stm:STM3241 0. tdcE; pyruvate formate-lyase 4/2-ketobutyrate formate-lyase K00656; COG: COG1882 Pyruvate-formate lyase; Psort location: Cytoplasmic, score:9.97.
  
    0.502
CKO_04518
Hypothetical protein; KEGG: shn:Shewana3_3435 9.1e-10 transcriptional regulator, LysR family K06022; COG: COG0583 Transcriptional regulator; Psort location: Cytoplasmic, score:9.26; Belongs to the LysR transcriptional regulatory family.
  
  
 0.485
CKO_04513
Hypothetical protein; KEGG: ape:APE_1501.1 9.6e-24 ribonuclease UK114; COG: COG0251 Putative translation initiation inhibitor, yjgF family; Psort location: Cytoplasmic, score:8.96.
  
    0.480
CKO_04154
Hypothetical protein; KEGG: stm:STM2971 1.4e-235 sdaB; L-serine dehydratase (L-threonine deaminase 2) K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
  
 0.467
CKO_04512
Hypothetical protein; KEGG: spt:SPA3109 1.8e-221 tdcG; L-serine dehydratase K01752; COG: COG1760 L-serine deaminase; Belongs to the iron-sulfur dependent L-serine dehydratase family.
  
  
 0.458
cbpM
Hypothetical protein; Interacts with CbpA and inhibits both the DnaJ-like co- chaperone activity and the DNA binding activity of CbpA. Together with CbpA, modulates the activity of the DnaK chaperone system. Does not inhibit the co-chaperone activity of DnaJ.
  
     0.455
CKO_04511
Hypothetical protein; COG: COG0814 Amino acid permeases; Psort location: CytoplasmicMembrane, score:10.00.
 
    
0.429
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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