close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04588Hypothetical protein; COG: COG0697 Permeases of the drug/metabolite transporter (DMT) superfamily; Psort location: CytoplasmicMembrane, score:10.00. (321 aa)    
Predicted Functional Partners:
obg
Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.
  
    0.852
CKO_04585
Hypothetical protein.
       0.702
CKO_03173
COG: COG3015 Uncharacterized lipoprotein NlpE involved in copper resistance.
  
     0.676
rpmA
COG: COG0211 Ribosomal protein L27; Belongs to the bacterial ribosomal protein bL27 family.
     
 0.594
CKO_02303
Hypothetical protein; KEGG: eci:UTI89_C0819 3.0e-249 ybiP; hypothetical protein YbiP K00924; COG: COG2194 Predicted membrane-associated, metal-dependent hydrolase; Psort location: CytoplasmicMembrane, score:9.46.
  
     0.514
CKO_01421
Hypothetical protein; COG: NOG22391 non supervised orthologous group.
  
     0.508
ytfE
Hypothetical protein; Di-iron-containing protein involved in the repair of iron- sulfur clusters damaged by oxidative and nitrosative stress conditions.
  
     0.501
CKO_04558
Hypothetical protein; COG: COG0814 Amino acid permeases; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.462
CKO_04496
Hypothetical protein; KEGG: eci:UTI89_C1658 7.7e-06 ydcR; hypothetical protein YdcR K00811; COG: COG2186 Transcriptional regulators; Psort location: Cytoplasmic, score:8.96.
  
     0.452
CKO_02850
Hypothetical protein; COG: COG0814 Amino acid permeases; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.448
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (44%) [HD]