close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04601Hypothetical protein; Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8- phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate; Belongs to the KdsC family. (188 aa)    
Predicted Functional Partners:
CKO_04600
Hypothetical protein; KEGG: stm:STM3315 3.0e-162 yrbH; putative sugar phosphate isomerase K06041; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: Cytoplasmic, score:8.96.
  
 0.991
kdsA
Hypothetical protein; KEGG: ecc:c1674 1.9e-144 kdsA; 2-dehydro-3-deoxyphosphooctonate aldolase (KDO 8-P synthase) K01627; COG: COG2877 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase; Psort location: Cytoplasmic, score:8.96; Belongs to the KdsA family.
  
 0.988
kdsB
Hypothetical protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
 
  
 0.976
lptC
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. Facilitates the transfer of LPS from the inner membrane to the periplasmic protein LptA. Could be a docking site for LptA. Belongs to the LptC family.
  
  
 0.925
CKO_04604
Hypothetical protein; KEGG: pen:PSEEN1094 1.0e-83 ABC transporter, ATP-binding protein; COG: COG1137 ABC-type (unclassified) transport system, ATPase component; Psort location: Cytoplasmic, score:9.12.
 
  
 0.906
CKO_04062
Hypothetical protein; KEGG: eci:UTI89_C3070 4.2e-156 gutQ; GutQ protein K02467; COG: COG0794 Predicted sugar phosphate isomerase involved in capsule formation; Psort location: Cytoplasmic, score:8.96.
  
 0.896
lptA
Hypothetical protein; Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm.
 
  
 0.850
CKO_04599
Hypothetical protein; COG: COG0530 Ca2+/Na+ antiporter; Psort location: CytoplasmicMembrane, score:10.00.
     
 0.753
lpxC
Hypothetical protein; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family.
 
   
 0.703
CKO_03185
Hypothetical protein; KEGG: ssn:SSO_0193 1.4e-77 lpxA; UDP-N-acetylglucosamine acetyltransferase; lipid A biosynthesis K00677; COG: COG1043 Acyl-[acyl carrier protein]--UDP-N-acetylglucosamine O-acyltransferase; Psort location: Cytoplasmic, score:9.97.
 
   
 0.684
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (38%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.