Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nanKHypothetical protein; Catalyzes the phosphorylation of N-acetylmannosamine (ManNAc) to ManNAc-6-P; Belongs to the ROK (NagC/XylR) family. NanK subfamily. (290 aa)    
Predicted Functional Partners:
nanE
Hypothetical protein; Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N- acetylglucosamine-6-phosphate (GlcNAc-6-P).
 
 0.998
nanA
Hypothetical protein; Catalyzes the reversible aldol cleavage of N-acetylneuraminic acid (sialic acid; Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate.
 
 
 0.984
nanT
Hypothetical protein; Catalyzes the proton-dependent transport of sialic acid. Belongs to the major facilitator superfamily. Sialate:H(+) symporter (SHS) (TC 2.A.1.12) family.
 
  
 0.881
CKO_02485
Hypothetical protein; KEGG: spt:SPA2056 0. nagE; pts system, N-acetylglucosamine-specific IIABC component K02802:K02803:K02804; COG: COG2190 Phosphotransferase system IIA components; Psort location: CytoplasmicMembrane, score:10.00.
  
 
 0.856
CKO_00736
Hypothetical protein; KEGG: ecp:ECP_2089 1.3e-248 mannose-1-phosphate guanylyltransferase K00971; COG: COG0662 Mannose-6-phosphate isomerase; Psort location: Cytoplasmic, score:8.96.
    
 0.847
CKO_04624
Hypothetical protein; COG: COG2731 Beta-galactosidase, beta subunit; Psort location: Cytoplasmic, score:8.96.
 
  
 0.825
CKO_00745
Hypothetical protein; KEGG: sty:STY2308 7.4e-152 galF; UTP-glucose-1-phosphate uridylyltransferase K00963; COG: COG1210 UDP-glucose pyrophosphorylase.
  
 
 0.813
CKO_01314
Hypothetical protein; KEGG: sty:STY1298 4.9e-155 galU; glucose-1-phosphate uridylyltransferase K00963; COG: COG1210 UDP-glucose pyrophosphorylase; Psort location: Cytoplasmic, score:8.96.
    
 0.808
glmU
Hypothetical protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat family.
     
 0.806
CKO_00130
Hypothetical protein; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family.
     
 0.806
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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