STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
argR-2Hypothetical protein; Regulates arginine biosynthesis genes. (156 aa)    
Predicted Functional Partners:
argA
Hypothetical protein; KEGG: ecj:JW2786 1.3e-211 argA; fused acetylglutamate kinase homolog (inactive) and amino acid N-acetyltransferase K00619; COG: COG0548 Acetylglutamate kinase; Psort location: Cytoplasmic, score:8.96; Belongs to the acetyltransferase family. ArgA subfamily.
  
  
 0.896
argH
Hypothetical protein; KEGG: ssn:SSO_4133 2.5e-231 argH; argininosuccinate lyase K01755; COG: COG0165 Argininosuccinate lyase; Psort location: Cytoplasmic, score:8.96.
  
  
 0.873
argC
Hypothetical protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily.
  
  
 0.873
argG
Hypothetical protein; KEGG: sty:STY3470 1.8e-237 argG; argininosuccinate synthetase K01940; COG: COG0137 Argininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
  
  
 0.872
argB
Hypothetical protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate.
  
  
 0.868
argI
Hypothetical protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.733
argI-2
Hypothetical protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
  
  
 0.733
metJ
Hypothetical protein; This regulatory protein, when combined with SAM (S- adenosylmethionine) represses the expression of the methionine regulon and of enzymes involved in SAM synthesis; Belongs to the MetJ family.
  
   
 0.723
proQ
Hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
     0.685
CKO_00500
COG: COG3092 Uncharacterized protein conserved in bacteria.
  
     0.683
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: high (82%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.