close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04644Hypothetical protein; COG: NOG12178 non supervised orthologous group. (87 aa)    
Predicted Functional Partners:
CKO_02318
Hypothetical protein; COG: NOG10254 non supervised orthologous group.
  
   
 0.772
CKO_03401
Hypothetical protein; KEGG: ece:Z5988 8.8e-101 putative lipoate-protein ligase A K03800:K07186; COG: COG3726 Uncharacterized membrane protein affecting hemolysin expression.
  
     0.772
CKO_02690
Hypothetical protein; COG: NOG09846 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.770
CKO_01332
Hypothetical protein; COG: NOG06197 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:10.00.
  
     0.766
ftsN
Hypothetical protein; Essential cell division protein that activates septal peptidoglycan synthesis and constriction of the cell. Acts on both sides of the membrane, via interaction with FtsA in the cytoplasm and interaction with the FtsQBL complex in the periplasm. These interactions may induce a conformational switch in both FtsA and FtsQBL, leading to septal peptidoglycan synthesis by FtsI and associated synthases.
  
     0.765
lpoB
Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b).
  
     0.763
CKO_01952
Hypothetical protein; COG: COG5633 Predicted periplasmic lipoprotein.
  
     0.763
CKO_03087
Hypothetical protein; COG: COG3678 P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein; Psort location: Periplasmic, score:10.00.
  
     0.759
CKO_01651
Hypothetical protein; COG: COG3895 Predicted periplasmic protein.
  
     0.756
mzrA
Hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.755
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: medium (46%) [HD]