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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
aaeAHypothetical protein; Forms an efflux pump with AaeB; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family. (310 aa)    
Predicted Functional Partners:
aaeB
Hypothetical protein; Forms an efflux pump with AaeA. Could function as a metabolic relief valve, allowing to eliminate certain compounds when they accumulate to high levels in the cell; Belongs to the aromatic acid exporter ArAE (TC 2.A.85) family.
 
  
 0.976
aaeX
Hypothetical protein; COG: NOG13538 non supervised orthologous group.
 
    0.919
macB
Hypothetical protein; Part of the tripartite efflux system MacAB-TolC. MacB is a non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides.
  
 
 0.903
CKO_02835
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.677
CKO_00657
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.658
CKO_02614
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.634
CKO_01443
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.633
CKO_04035
Hypothetical protein; KEGG: sgl:SG1466 1.5e-06 dethiobiotin synthase K01935; COG: COG0477 Permeases of the major facilitator superfamily; Psort location: CytoplasmicMembrane, score:10.00.
  
 
 0.631
CKO_04427
COG: COG1538 Outer membrane protein; Psort location: OuterMembrane, score:10.00.
 
 
 0.612
CKO_04649
Hypothetical protein.
       0.572
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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