close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04655Hypothetical protein; KEGG: spt:SPA3237 1.9e-254 rnG; ribonuclease G K08301; COG: COG1530 Ribonucleases G and E; Psort location: Cytoplasmic, score:9.97. (489 aa)    
Predicted Functional Partners:
CKO_04656
Hypothetical protein; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
    0.898
pnp
Hypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
  
 
 0.832
CKO_00214
Hypothetical protein; KEGG: ecp:ECP_2570 5.0e-169 signal peptidase I K03100; COG: COG0681 Signal peptidase I; Psort location: CytoplasmicMembrane, score:10.00; Belongs to the peptidase S26 family.
  
    0.818
CKO_04657
Hypothetical protein; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family.
       0.800
CKO_04658
Hypothetical protein; Involved in formation and maintenance of cell shape.
       0.800
rapZ
Hypothetical protein; Modulates the synthesis of GlmS, by affecting the processing and stability of the regulatory small RNA GlmZ. When glucosamine-6- phosphate (GlcN6P) concentrations are high in the cell, RapZ binds GlmZ and targets it to cleavage by RNase E. Consequently, GlmZ is inactivated and unable to activate GlmS synthesis. Under low GlcN6P concentrations, RapZ is sequestered and inactivated by an other regulatory small RNA, GlmY, preventing GlmZ degradation and leading to synthesis of GlmS; Belongs to the RapZ-like family. RapZ subfamily.
 
 
 
 0.758
eno
Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 
 0.681
eno-2
Hypothetical protein; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
    
 
 0.681
CKO_04654
COG: COG3164 Predicted membrane protein; Psort location: OuterMembrane, score:9.52.
       0.672
CKO_04659
Hypothetical protein; KEGG: hpa:HPAG1_1318 1.5e-91 rod shape-determining protein K01529; COG: COG1077 Actin-like ATPase involved in cell morphogenesis; Psort location: Cytoplasmic, score:9.97.
       0.631
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
Server load: low (32%) [HD]