| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_03804 | CKO_03812 | CKO_03804 | CKO_03812 | Hypothetical protein; KEGG: eci:UTI89_C1133 1.3e-15 hypothetical protein; COG: COG0790 FOG: TPR repeat, SEL1 subfamily. | Hypothetical protein; KEGG: pmu:PM0023 0.0014 nrfA; nitrite reductase periplasmic cytochrome c552 K03385; COG: NOG06794 non supervised orthologous group. | 0.547 |
| CKO_03804 | CKO_04674 | CKO_03804 | CKO_04674 | Hypothetical protein; KEGG: eci:UTI89_C1133 1.3e-15 hypothetical protein; COG: COG0790 FOG: TPR repeat, SEL1 subfamily. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.455 |
| CKO_03812 | CKO_03804 | CKO_03812 | CKO_03804 | Hypothetical protein; KEGG: pmu:PM0023 0.0014 nrfA; nitrite reductase periplasmic cytochrome c552 K03385; COG: NOG06794 non supervised orthologous group. | Hypothetical protein; KEGG: eci:UTI89_C1133 1.3e-15 hypothetical protein; COG: COG0790 FOG: TPR repeat, SEL1 subfamily. | 0.547 |
| CKO_03812 | CKO_04674 | CKO_03812 | CKO_04674 | Hypothetical protein; KEGG: pmu:PM0023 0.0014 nrfA; nitrite reductase periplasmic cytochrome c552 K03385; COG: NOG06794 non supervised orthologous group. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.463 |
| CKO_04674 | CKO_03804 | CKO_04674 | CKO_03804 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; KEGG: eci:UTI89_C1133 1.3e-15 hypothetical protein; COG: COG0790 FOG: TPR repeat, SEL1 subfamily. | 0.455 |
| CKO_04674 | CKO_03812 | CKO_04674 | CKO_03812 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; KEGG: pmu:PM0023 0.0014 nrfA; nitrite reductase periplasmic cytochrome c552 K03385; COG: NOG06794 non supervised orthologous group. | 0.463 |
| CKO_04674 | CKO_04675 | CKO_04674 | CKO_04675 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; COG: NOG13902 non supervised orthologous group. | 0.588 |
| CKO_04674 | CKO_04808 | CKO_04674 | CKO_04808 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; KEGG: stm:STM3484 2.4e-130 dam; DNA adenine methylase K06223; COG: COG0338 Site-specific DNA methylase. | 0.579 |
| CKO_04674 | dusB | CKO_04674 | CKO_04672 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | 0.495 |
| CKO_04674 | fis | CKO_04674 | CKO_04673 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.543 |
| CKO_04674 | lexA | CKO_04674 | CKO_03872 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. Binds to the 16 bp palindromic sequence 5'-CTGTATATATATACAG-3'. In the presence of single- stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.579 |
| CKO_04674 | sucC | CKO_04674 | CKO_02431 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.546 |
| CKO_04674 | sucC-2 | CKO_04674 | CKO_03851 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. | 0.546 |
| CKO_04674 | sucD | CKO_04674 | CKO_02429 | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | Hypothetical protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.448 |
| CKO_04675 | CKO_04674 | CKO_04675 | CKO_04674 | Hypothetical protein; COG: NOG13902 non supervised orthologous group. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.588 |
| CKO_04675 | fis | CKO_04675 | CKO_04673 | Hypothetical protein; COG: NOG13902 non supervised orthologous group. | Hypothetical protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.425 |
| CKO_04808 | CKO_04674 | CKO_04808 | CKO_04674 | Hypothetical protein; KEGG: stm:STM3484 2.4e-130 dam; DNA adenine methylase K06223; COG: COG0338 Site-specific DNA methylase. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.579 |
| dusB | CKO_04674 | CKO_04672 | CKO_04674 | Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.495 |
| dusB | fis | CKO_04672 | CKO_04673 | Hypothetical protein; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the Dus family. DusB subfamily. | Hypothetical protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | 0.970 |
| fis | CKO_04674 | CKO_04673 | CKO_04674 | Hypothetical protein; Activates ribosomal RNA transcription. Plays a direct role in upstream activation of rRNA promoters; Belongs to the transcriptional regulatory Fis family. | Hypothetical protein; KEGG: sec:SC3324 3.2e-135 yhdJ; putative methyltransferase K07319; COG: COG0863 DNA modification methylase; Belongs to the N(4)/N(6)-methyltransferase family. | 0.543 |