Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
smgCOG: COG2922 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the Smg family. (152 aa)    
Predicted Functional Partners:
CKO_04698
Hypothetical protein; COG: COG0758 Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake.
     
 0.831
CKO_04696
Hypothetical protein; KEGG: cvi:CV4269 3.9e-44 topA; DNA topoisomerase K03168; COG: COG0551 Zn-finger domain associated with topoisomerase type I; Psort location: Cytoplasmic, score:8.96.
 
   
 0.807
CKO_04693
Hypothetical protein; COG: NOG13911 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
       0.770
aroE
Hypothetical protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).
       0.770
tsaC
Hypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate.
       0.770
zapD
Hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity.
  
     0.718
CKO_02513
Hypothetical protein; COG: NOG08739 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.696
def
Hypothetical protein; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
  
    0.642
CKO_01174
Hypothetical protein; COG: COG3065 Starvation-inducible outer membrane lipoprotein.
  
     0.634
CKO_03188
COG: COG2825 Outer membrane protein; Psort location: OuterMembrane, score:9.92; Belongs to the skp family.
  
    0.628
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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