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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tusCHypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. (119 aa)    
Predicted Functional Partners:
CKO_04749
Hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions.
 
 0.999
tusD
Hypothetical protein; Part of a sulfur-relay system required for 2-thiolation of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE.
 
 0.999
CKO_01288
Hypothetical protein; COG: COG1553 Uncharacterized conserved protein involved in intracellular sulfur reduction.
  
 
 0.915
CKO_02097
Hypothetical protein; Part of a sulfur-relay system.
 
  
 0.830
CKO_04752
COG: COG2964 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96.
  
    0.808
tusA
Hypothetical protein; Sulfur carrier protein involved in sulfur trafficking in the cell. Part of a sulfur-relay system required for 2-thiolation during synthesis of 2-thiouridine of the modified wobble base 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) in tRNA. Interacts with IscS and stimulates its cysteine desulfurase activity. Accepts an activated sulfur from IscS, which is then transferred to TusD, and thus determines the direction of sulfur flow from IscS to 2-thiouridine formation. Also appears to be involved in sulfur transfer for the biosynthesis of molybdopterin.
 
   
 0.554
sprT
COG: COG3091 Uncharacterized protein conserved in bacteria; Belongs to the SprT family.
  
     0.516
CKO_04753
Hypothetical protein; KEGG: stm:STM3453 9.0e-131 fkpA; FKBP-type peptidyl-prolyl cis-trans isomerase (rotamase) K03772; COG: COG0545 FKBP-type peptidyl-prolyl cis-trans isomerases 1; Psort location: Periplasmic, score:10.00.
       0.493
CKO_01055
Hypothetical protein; Required for resistance to DNA-damaging agents. Belongs to the universal stress protein A family.
  
     0.488
slyX
COG: COG2900 Uncharacterized protein conserved in bacteria; Psort location: Cytoplasmic, score:8.96; Belongs to the SlyX family.
 
     0.481
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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