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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04757Hypothetical protein; COG: COG3529 Predicted nucleic-acid-binding protein containing a Zn-ribbon domain; Psort location: Cytoplasmic, score:8.96. (66 aa)    
Predicted Functional Partners:
kefB
Hypothetical protein; Pore-forming subunit of a potassium efflux system that confers protection against electrophiles. Catalyzes K(+)/H(+) antiport.
       0.816
kefG
Hypothetical protein; Regulatory subunit of a potassium efflux system that confers protection against electrophiles. Required for full activity of KefB.
       0.800
CKO_00460
Hypothetical protein; COG: NOG13546 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.745
CKO_00587
COG: COG3082 Uncharacterized protein conserved in bacteria; Belongs to the UPF0352 family.
  
     0.725
CKO_00500
COG: COG3092 Uncharacterized protein conserved in bacteria.
  
     0.708
seqA
Hypothetical protein; Negative regulator of replication initiation, which contributes to regulation of DNA replication and ensures that replication initiation occurs exactly once per chromosome per cell cycle. Binds to pairs of hemimethylated GATC sequences in the oriC region, thus preventing assembly of replication proteins and re- initiation at newly replicated origins. Repression is relieved when the region becomes fully methylated.
  
     0.700
syd
Hypothetical protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.691
mutH
Hypothetical protein; Sequence-specific endonuclease that cleaves unmethylated GATC sequences. It is involved in DNA mismatch repair; Belongs to the MutH family.
  
     0.681
fadR
Hypothetical protein; Multifunctional regulator of fatty acid metabolism.
  
     0.677
proQ
Hypothetical protein; RNA chaperone with significant RNA binding, RNA strand exchange and RNA duplexing activities. May regulate ProP activity through an RNA-based, post-transcriptional mechanism. Belongs to the ProQ family.
  
    0.649
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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