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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CKO_04819Hypothetical protein; KEGG: stm:STM3493 0. mrcA; transpeptidase of penicillin-binding protein 1a (peptidoglycan synthetase) K05366; COG: COG5009 Membrane carboxypeptidase/penicillin-binding protein. (858 aa)    
Predicted Functional Partners:
CKO_03220
Hypothetical protein; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).
 
 
0.956
CKO_00263
Hypothetical protein; KEGG: ecc:c3042 0. pbpC; penicillin-binding protein 1C K05367; COG: COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC; Psort location: CytoplasmicMembrane, score:10.00.
  
  
0.922
CKO_02526
Hypothetical protein; KEGG: sec:SC0666 1.8e-212 dacA; D-alanyl-D-alanine carboxypeptidase, penicillin-binding protein 5 K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.922
CKO_00774
Hypothetical protein; KEGG: stm:STM2062 5.8e-191 dacD; DD-carboxypeptidase, penicillin-binding protein 6b K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Psort location: CytoplasmicMembrane, score:8.60; Belongs to the peptidase S11 family.
     
 0.920
CKO_02270
Hypothetical protein; KEGG: ecc:c0924 1.3e-207 dacC; penicillin-binding protein 6 precursor K07258; COG: COG1686 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family.
     
 0.920
lpoA
Hypothetical protein; Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1A (PBP1a). Belongs to the LpoA family.
  
 
 
 0.802
secD
Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.
 
     0.706
CKO_05107
Hypothetical protein; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
    0.664
murC
Hypothetical protein; Cell wall formation; Belongs to the MurCDEF family.
  
   
 0.661
mrdA-2
Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.
  
 
 
 0.628
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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