| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| CKO_00863 | CKO_01375 | CKO_00863 | CKO_01375 | Hypothetical protein; KEGG: ecp:ECP_1976 3.3e-37 putative D-alanyl carrier protein K03367; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | 0.771 |
| CKO_00863 | bioH | CKO_00863 | CKO_04834 | Hypothetical protein; KEGG: ecp:ECP_1976 3.3e-37 putative D-alanyl carrier protein K03367; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.591 |
| CKO_01375 | CKO_00863 | CKO_01375 | CKO_00863 | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | Hypothetical protein; KEGG: ecp:ECP_1976 3.3e-37 putative D-alanyl carrier protein K03367; Psort location: Cytoplasmic, score:8.96. | 0.771 |
| CKO_01375 | CKO_04911 | CKO_01375 | CKO_04911 | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | Hypothetical protein; KEGG: hpa:HPAG1_0538 0.00049 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score:8.96. | 0.771 |
| CKO_01375 | acpP | CKO_01375 | CKO_01964 | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.825 |
| CKO_01375 | bioH | CKO_01375 | CKO_04834 | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.922 |
| CKO_04833 | bioH | CKO_04833 | CKO_04834 | Hypothetical protein; KEGG: reh:H16_A0339 3.9e-27 predicted amidophosphoribosyltransferase; COG: COG1040 Predicted amidophosphoribosyltransferases. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.622 |
| CKO_04911 | CKO_01375 | CKO_04911 | CKO_01375 | Hypothetical protein; KEGG: hpa:HPAG1_0538 0.00049 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | 0.771 |
| CKO_04911 | acpP | CKO_04911 | CKO_01964 | Hypothetical protein; KEGG: hpa:HPAG1_0538 0.00049 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | 0.923 |
| CKO_04911 | bioH | CKO_04911 | CKO_04834 | Hypothetical protein; KEGG: hpa:HPAG1_0538 0.00049 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score:8.96. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.591 |
| acpP | CKO_01375 | CKO_01964 | CKO_01375 | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Hypothetical protein; KEGG: sty:STY1352 1.0e-131 fabI; enoyl-[acyl-carrier-protein] reductase (NADH) K00208; COG: COG0623 Enoyl-[acyl-carrier-protein] reductase (NADH); Psort location: Cytoplasmic, score:9.26. | 0.825 |
| acpP | CKO_04911 | CKO_01964 | CKO_04911 | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Hypothetical protein; KEGG: hpa:HPAG1_0538 0.00049 acyl carrier protein K01162; COG: COG0236 Acyl carrier protein; Psort location: Cytoplasmic, score:8.96. | 0.923 |
| acpP | bioH | CKO_01964 | CKO_04834 | Hypothetical protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.854 |
| apaH | bioH | CKO_03331 | CKO_04834 | Hypothetical protein; Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP; Belongs to the Ap4A hydrolase family. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.766 |
| bioC | bioD | CKO_02351 | CKO_01592 | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. | 0.935 |
| bioC | bioF | CKO_02351 | CKO_02352 | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Hypothetical protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.979 |
| bioC | bioH | CKO_02351 | CKO_04834 | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Hypothetical protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.974 |
| bioC | kbl | CKO_02351 | CKO_05077 | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | Hypothetical protein; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.872 |
| bioD | bioC | CKO_01592 | CKO_02351 | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. | Hypothetical protein; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.935 |
| bioD | bioF | CKO_01592 | CKO_02352 | Hypothetical protein; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. | Hypothetical protein; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.950 |