Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
wecHHypothetical protein; Responsible for the incorporation of O-acetyl groups into the enterobacterial common antigen (ECA) trisaccharide repeat units. (331 aa)    
Predicted Functional Partners:
mdoC
Hypothetical protein; Necessary for the succinyl substitution of periplasmic glucans. Could catalyze the transfer of succinyl residues from the cytoplasmic side of the membrane to the nascent glucan backbones on the periplasmic side of the membrane.
 
   
 0.825
CKO_02781
Hypothetical protein; COG: NOG06193 non supervised orthologous group; Psort location: Cytoplasmic, score:8.96.
  
     0.757
secM
Hypothetical protein; Regulates secA expression by translational coupling of the secM secA operon. Translational pausing at a specific Pro residue 5 residues before the end of the protein may allow disruption of a mRNA repressor helix that normally suppresses secA translation initiation. Belongs to the SecM family.
  
     0.752
CKO_01158
COG: COG4811 Predicted membrane protein.
  
     0.736
CKO_01638
Hypothetical protein; COG: NOG08686 non supervised orthologous group; Psort location: CytoplasmicMembrane, score:9.50.
  
     0.735
CKO_01374
Hypothetical protein; COG: COG2128 Uncharacterized conserved protein.
  
     0.734
mzrA
Hypothetical protein; Modulates the activity of the EnvZ/OmpR two-component regulatory system, probably by directly modulating EnvZ enzymatic activity and increasing stability of phosphorylated OmpR.
  
     0.725
CKO_04114
Hypothetical protein; KEGG: sfx:S2969 8.2e-169 iap; alkaline phosphatase isozyme conversion, aminopeptidase K01269; COG: COG2234 Predicted aminopeptidases.
  
     0.724
CKO_00327
Hypothetical protein; COG: NOG10065 non supervised orthologous group.
  
     0.721
CKO_01942
Hypothetical protein; KEGG: reu:Reut_B4338 0.0030 copper/zinc superoxide dismutase K04565; COG: NOG13874 non supervised orthologous group.
  
     0.709
Your Current Organism:
Citrobacter koseri
NCBI taxonomy Id: 290338
Other names: C. koseri ATCC BAA-895, Citrobacter (diversus) koseri ATCC BAA-895, Citrobacter koseri ATCC BAA-895, Citrobacter koseri str. ATCC BAA-895, Citrobacter koseri strain ATCC BAA-895
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