node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAur_1588 | AAur_4203 | AAur_1588 | AAur_4203 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.874 |
AAur_1588 | dnaA | AAur_1588 | AAur_0001 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.758 |
AAur_1588 | dnaN | AAur_1588 | AAur_0002 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.593 |
AAur_1588 | nusG | AAur_1588 | AAur_2966 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.677 |
AAur_1588 | recA | AAur_1588 | AAur_1594 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.442 |
AAur_1588 | rpoB | AAur_1588 | AAur_2957 | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | DNA-directed RNA polymerase, beta subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.438 |
AAur_4203 | AAur_1588 | AAur_4203 | AAur_1588 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | 0.874 |
AAur_4203 | dnaA | AAur_4203 | AAur_0001 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | 0.786 |
AAur_4203 | dnaB | AAur_4203 | AAur_4139 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.577 |
AAur_4203 | dnaN | AAur_4203 | AAur_0002 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.629 |
AAur_4203 | nusG | AAur_4203 | AAur_2966 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.610 |
AAur_4203 | recF | AAur_4203 | AAur_0004 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Putative DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. | 0.509 |
AAur_4203 | rpmH | AAur_4203 | AAur_4209 | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | Ribosomal protein L34; Identified by match to protein family HMM PF00468; match to protein family HMM TIGR01030; Belongs to the bacterial ribosomal protein bL34 family. | 0.472 |
dnaA | AAur_1588 | AAur_0001 | AAur_1588 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Identified by match to protein family HMM PF01580; Belongs to the FtsK/SpoIIIE/SftA family. | 0.758 |
dnaA | AAur_4203 | AAur_0001 | AAur_4203 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Putative chromosome partitioning protein (ParB); Identified by match to protein family HMM PF02195; match to protein family HMM TIGR00180; Belongs to the ParB family. | 0.786 |
dnaA | dnaB | AAur_0001 | AAur_4139 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. | 0.923 |
dnaA | dnaN | AAur_0001 | AAur_0002 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.989 |
dnaA | gyrB | AAur_0001 | AAur_0006 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.792 |
dnaA | nusG | AAur_0001 | AAur_2966 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | Transcription termination/antitermination factor NusG; Participates in transcription elongation, termination and antitermination. | 0.746 |
dnaA | recA | AAur_0001 | AAur_1594 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. | recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.762 |