node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
acsA | acsA-2 | AAur_1375 | AAur_3353 | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.900 |
acsA | gltA-2 | AAur_1375 | AAur_2795 | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.957 |
acsA | pckG | AAur_1375 | AAur_0832 | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.836 |
acsA | pyc | AAur_1375 | AAur_1686 | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.865 |
acsA-2 | acsA | AAur_3353 | AAur_1375 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | 0.900 |
acsA-2 | gltA-2 | AAur_3353 | AAur_2795 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | 0.957 |
acsA-2 | pckG | AAur_3353 | AAur_0832 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.836 |
acsA-2 | pyc | AAur_3353 | AAur_1686 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.865 |
eno | mdh | AAur_1263 | AAur_0570 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.678 |
eno | pckG | AAur_1263 | AAur_0832 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.914 |
eno | ppc | AAur_1263 | AAur_0764 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.930 |
eno | ppsA | AAur_1263 | AAur_1894 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.914 |
eno | pyc | AAur_1263 | AAur_1686 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.511 |
eno | pyk | AAur_1263 | AAur_1844 | Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.995 |
gltA-2 | acsA | AAur_2795 | AAur_1375 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | acetate--CoA ligase; Identified by match to protein family HMM PF00501; match to protein family HMM TIGR02188. | 0.957 |
gltA-2 | acsA-2 | AAur_2795 | AAur_3353 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.957 |
gltA-2 | mdh | AAur_2795 | AAur_0570 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. | 0.987 |
gltA-2 | mqo | AAur_2795 | AAur_2520 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | Malate:quinone-oxidoreductase; Identified by match to protein family HMM PF01266; match to protein family HMM PF06039; match to protein family HMM TIGR01320. | 0.956 |
gltA-2 | pckG | AAur_2795 | AAur_0832 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxykinase; Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle; Belongs to the phosphoenolpyruvate carboxykinase [GTP] family. | 0.927 |
gltA-2 | ppc | AAur_2795 | AAur_0764 | Citrate synthase I; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01798; Belongs to the citrate synthase family. | Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. | 0.880 |