STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Gene Fusion
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[Homology]
Score
Adeh_0476(NiFe) hydrogenase maturation protein HypF; Involved in the maturation of [NiFe] hydrogenases. Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of [NiFe]-hydrogenases. HypF functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide. (773 aa)    
Predicted Functional Partners:
Adeh_0473
Hydrogenase expression/formation protein HypE.
 
 
 0.991
Adeh_0474
Hydrogenase formation HypD protein; Belongs to the HypD family.
 
  
 0.966
Adeh_0475
Hydrogenase assembly chaperone hypC/hupF.
 
 
 0.966
Adeh_0471
Hydrogenase accessory protein HypB.
 
   
 0.942
Adeh_0477
Peptidase M52, hydrogen uptake protein.
 
   
 0.905
Adeh_0478
Nickel-dependent hydrogenase, large subunit; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
 
 
 
 0.899
Adeh_0481
Hydrogenase (NiFe) small subunit (hydA).
 
 
 
 0.897
hypA
Hydrogenase expression/synthesis, HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.820
Adeh_4162
Nickel-dependent hydrogenase, large subunit.
 
   
 0.815
Adeh_4161
Peptidase M52, hydrogen uptake protein.
 
   
 0.753
Your Current Organism:
Anaeromyxobacter dehalogenans
NCBI taxonomy Id: 290397
Other names: A. dehalogenans 2CP-C, Anaeromyxobacter dehalogenans 2CP-C, Anaeromyxobacter dehalogenans ATCC BAA-259, Anaeromyxobacter dehalogenans str. 2CP-C, Anaeromyxobacter dehalogenans strain 2CP-C
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