node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adeh_0002 | dut | Adeh_0002 | Adeh_1108 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.839 |
Adeh_1552 | Adeh_1870 | Adeh_1552 | Adeh_1870 | Zinc-binding CMP/dCMP deaminase. | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | 0.901 |
Adeh_1552 | Adeh_3107 | Adeh_1552 | Adeh_3107 | Zinc-binding CMP/dCMP deaminase. | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | 0.904 |
Adeh_1552 | dut | Adeh_1552 | Adeh_1108 | Zinc-binding CMP/dCMP deaminase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.947 |
Adeh_1552 | surE | Adeh_1552 | Adeh_0753 | Zinc-binding CMP/dCMP deaminase. | 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
Adeh_1552 | thyX | Adeh_1552 | Adeh_1139 | Zinc-binding CMP/dCMP deaminase. | Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.911 |
Adeh_1552 | tmk | Adeh_1552 | Adeh_1721 | Zinc-binding CMP/dCMP deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
Adeh_1552 | tmk-2 | Adeh_1552 | Adeh_3313 | Zinc-binding CMP/dCMP deaminase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.925 |
Adeh_1870 | Adeh_1552 | Adeh_1870 | Adeh_1552 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Zinc-binding CMP/dCMP deaminase. | 0.901 |
Adeh_1870 | Adeh_3107 | Adeh_1870 | Adeh_3107 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | 0.903 |
Adeh_1870 | dut | Adeh_1870 | Adeh_1108 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.916 |
Adeh_1870 | surE | Adeh_1870 | Adeh_0753 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.902 |
Adeh_1870 | thyX | Adeh_1870 | Adeh_1139 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Thymidylate synthase (FAD); Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. | 0.900 |
Adeh_1870 | tmk | Adeh_1870 | Adeh_1721 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.900 |
Adeh_1870 | tmk-2 | Adeh_1870 | Adeh_3313 | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.900 |
Adeh_2372 | dut | Adeh_2372 | Adeh_1108 | Phosphopantothenate-cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.976 |
Adeh_3107 | Adeh_1552 | Adeh_3107 | Adeh_1552 | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | Zinc-binding CMP/dCMP deaminase. | 0.904 |
Adeh_3107 | Adeh_1870 | Adeh_3107 | Adeh_1870 | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | HAD superfamily (subfamily IG) hydrolase, 5'-Nucleotidase. | 0.903 |
Adeh_3107 | dut | Adeh_3107 | Adeh_1108 | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Adeh_3107 | surE | Adeh_3107 | Adeh_0753 | Metallophosphoesterase; Belongs to the 5'-nucleotidase family. | 5'-nucleotidase / 3'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.915 |