STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Adeh_3689Hypothetical protein. (611 aa)    
Predicted Functional Partners:
Adeh_1549
Heat shock protein 70.
 
 0.687
Adeh_2689
Heat shock protein 70.
 
 0.683
Adeh_1807
Heat shock protein 70.
 
 0.681
dnaK-2
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.681
Adeh_1536
Conserved region 2266; Belongs to the heat shock protein 70 family.
 
 0.680
Adeh_2350
Conserved region 2266; Belongs to the heat shock protein 70 family.
 
 0.678
Adeh_0597
Fe-S protein assembly chaperone HscA; Belongs to the heat shock protein 70 family.
 
 0.676
Adeh_2588
Heat shock protein 70.
 
 0.675
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
 
 0.670
grpE-2
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
 
 
 0.652
Your Current Organism:
Anaeromyxobacter dehalogenans
NCBI taxonomy Id: 290397
Other names: A. dehalogenans 2CP-C, Anaeromyxobacter dehalogenans 2CP-C, Anaeromyxobacter dehalogenans ATCC BAA-259, Anaeromyxobacter dehalogenans str. 2CP-C, Anaeromyxobacter dehalogenans strain 2CP-C
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