node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_1535 | Arth_3302 | Arth_1535 | Arth_3302 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.704 |
Arth_1535 | aroA | Arth_1535 | Arth_2653 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.710 |
Arth_1535 | aroB | Arth_1535 | Arth_2272 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.876 |
Arth_1535 | aroC | Arth_1535 | Arth_2274 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.901 |
Arth_1535 | aroK | Arth_1535 | Arth_2273 | Prephenate dehydrogenase; PFAM: amino acid-binding ACT domain protein; Prephenate dehydrogenase; KEGG: lxx:Lxx05720 prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.755 |
Arth_1553 | Arth_2275 | Arth_1553 | Arth_2275 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | 0.459 |
Arth_1553 | Arth_3302 | Arth_1553 | Arth_3302 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.913 |
Arth_1553 | aroA | Arth_1553 | Arth_2653 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.508 |
Arth_1553 | aroB | Arth_1553 | Arth_2272 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.969 |
Arth_1553 | aroC | Arth_1553 | Arth_2274 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.480 |
Arth_1553 | aroQ | Arth_1553 | Arth_3392 | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | 3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.436 |
Arth_2271 | Arth_2275 | Arth_2271 | Arth_2275 | Hypothetical protein. | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | 0.705 |
Arth_2271 | aroB | Arth_2271 | Arth_2272 | Hypothetical protein. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.794 |
Arth_2271 | aroC | Arth_2271 | Arth_2274 | Hypothetical protein. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.811 |
Arth_2271 | aroK | Arth_2271 | Arth_2273 | Hypothetical protein. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.787 |
Arth_2271 | mltG | Arth_2271 | Arth_2276 | Hypothetical protein. | Aminodeoxychorismate lyase; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. | 0.706 |
Arth_2275 | Arth_1553 | Arth_2275 | Arth_1553 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; KEGG: lxx:Lxx15410 2-dehydro-3-deoxyphosphoheptonate aldolase; TIGRFAM: phospho-2-dehydro-3-deoxyheptonate aldolase; PFAM: DAHP synthetase, class II; Belongs to the class-II DAHP synthase family. | 0.459 |
Arth_2275 | Arth_2271 | Arth_2275 | Arth_2271 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | Hypothetical protein. | 0.705 |
Arth_2275 | Arth_3302 | Arth_2275 | Arth_3302 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). | 0.415 |
Arth_2275 | aroA | Arth_2275 | Arth_2653 | PFAM: Shikimate/quinate 5-dehydrogenase; Shikimate dehydrogenase substrate binding, N-terminal domain protein; KEGG: lxx:Lxx10940 shikimate 5-dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.989 |