node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arth_2090 | Arth_2300 | Arth_2090 | Arth_2300 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | 0.975 |
Arth_2090 | Arth_3047 | Arth_2090 | Arth_3047 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | 0.965 |
Arth_2090 | Arth_4169 | Arth_2090 | Arth_4169 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | 0.965 |
Arth_2090 | ffh | Arth_2090 | Arth_2489 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.968 |
Arth_2090 | ftsY | Arth_2090 | Arth_2494 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.985 |
Arth_2090 | secA | Arth_2090 | Arth_2706 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.994 |
Arth_2090 | secE | Arth_2090 | Arth_2996 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.998 |
Arth_2090 | secY | Arth_2090 | Arth_2956 | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.995 |
Arth_2300 | Arth_2090 | Arth_2300 | Arth_2090 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.975 |
Arth_2300 | Arth_3047 | Arth_2300 | Arth_3047 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | 0.916 |
Arth_2300 | Arth_4169 | Arth_2300 | Arth_4169 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | 0.916 |
Arth_2300 | ffh | Arth_2300 | Arth_2489 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.967 |
Arth_2300 | ftsY | Arth_2300 | Arth_2494 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Signal recognition particle-docking protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). | 0.967 |
Arth_2300 | secA | Arth_2300 | Arth_2706 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Protein translocase subunit secA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. | 0.966 |
Arth_2300 | secE | Arth_2300 | Arth_2996 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Protein translocase subunit secE/sec61 gamma; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. | 0.982 |
Arth_2300 | secY | Arth_2300 | Arth_2956 | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | Protein translocase subunit secY/sec61 alpha; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. | 0.969 |
Arth_3047 | Arth_2090 | Arth_3047 | Arth_2090 | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | Protein translocase subunit secG; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.965 |
Arth_3047 | Arth_2300 | Arth_3047 | Arth_2300 | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | TIGRFAM: preprotein translocase, YajC subunit; PFAM: YajC family protein; KEGG: lxx:Lxx10790 preprotein translocase, YajC subunit. | 0.916 |
Arth_3047 | Arth_4169 | Arth_3047 | Arth_4169 | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | 0.901 |
Arth_3047 | ffh | Arth_3047 | Arth_2489 | PFAM: 60 kDa inner membrane insertion protein; KEGG: lxx:Lxx25270 preprotein translocase, YidC subunit. | Signal recognition particle subunit FFH/SRP54 (srp54); Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. | 0.944 |