STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (341 aa)    
Predicted Functional Partners:
Arth_2095
PFAM: phosphoglucose isomerase (PGI); KEGG: lxx:Lxx11600 glucose-6-phosphate isomerase; Belongs to the GPI family.
 
 0.980
Arth_0518
Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family.
 
 
 0.963
Arth_1184
TIGRFAM: fructose-1,6-bisphosphatase, class II; PFAM: GlpX family protein; KEGG: sma:SAV3215 putative glycerol-inducible protein.
  
 
 0.951
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily.
  
 
 0.947
Arth_0275
PFAM: ketose-bisphosphate aldolase, class-II; KEGG: mta:Moth_0609 fructose-1,6-bisphosphate aldolase, class II.
 
 
 0.943
Arth_2097
TIGRFAM: transketolase; PFAM: Transketolase domain protein; Transketolase, central region; KEGG: lxx:Lxx11620 transketolase A; Belongs to the transketolase family.
  
 
 0.939
Arth_1712
KEGG: lxx:Lxx19340 tagatose-bisphosphate aldolase; TIGRFAM: ketose-bisphosphate aldolases; PFAM: ketose-bisphosphate aldolase, class-II.
  
 
 0.930
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
  
 0.926
Arth_3709
PFAM: sugar isomerase (SIS); KEGG: tko:TK0475 bifunctional D-arabino 3-hexulose-6-phosphate formaldehyde lyase/phosphohexuloisomerase.
    
 0.920
Arth_0053
PFAM: PfkB domain protein; KEGG: mpa:MAP0876c putative fructokinase.
  
 
 0.917
Your Current Organism:
Arthrobacter sp. FB24
NCBI taxonomy Id: 290399
Other names: A. sp. FB24
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