node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Jann_0089 | folD | Jann_0089 | Jann_0983 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.409 |
Jann_0089 | xseA | Jann_0089 | Jann_3300 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.614 |
Jann_0089 | xseB | Jann_0089 | Jann_0090 | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.893 |
Jann_2747 | polA | Jann_2747 | Jann_1683 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.581 |
Jann_2747 | uvrB | Jann_2747 | Jann_3602 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.506 |
Jann_2747 | uvrC | Jann_2747 | Jann_3919 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.508 |
Jann_2747 | xseA | Jann_2747 | Jann_3300 | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.639 |
Jann_3299 | Jann_3301 | Jann_3299 | Jann_3301 | Transcriptional regulator, TetR family. | Hypothetical protein. | 0.623 |
Jann_3299 | purD | Jann_3299 | Jann_3302 | Transcriptional regulator, TetR family. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.459 |
Jann_3299 | xseA | Jann_3299 | Jann_3300 | Transcriptional regulator, TetR family. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.631 |
Jann_3301 | Jann_3299 | Jann_3301 | Jann_3299 | Hypothetical protein. | Transcriptional regulator, TetR family. | 0.623 |
Jann_3301 | purD | Jann_3301 | Jann_3302 | Hypothetical protein. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.586 |
Jann_3301 | xseA | Jann_3301 | Jann_3300 | Hypothetical protein. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.811 |
folD | Jann_0089 | Jann_0983 | Jann_0089 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Farnesyl-diphosphate synthase; Belongs to the FPP/GGPP synthase family. | 0.409 |
folD | polA | Jann_0983 | Jann_1683 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.674 |
folD | purD | Jann_0983 | Jann_3302 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Phosphoribosylamine--glycine ligase; Belongs to the GARS family. | 0.595 |
folD | xseA | Jann_0983 | Jann_3300 | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.590 |
polA | Jann_2747 | Jann_1683 | Jann_2747 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | DNA replication and repair protein RecN; May be involved in recombinational repair of damaged DNA. | 0.581 |
polA | folD | Jann_1683 | Jann_0983 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Methenyltetrahydrofolate cyclohydrolase / 5,10-methylenetetrahydrofolate dehydrogenase (NADP+); Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.674 |
polA | uvrB | Jann_1683 | Jann_3602 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.770 |