STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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Textmining
[Homology]
Score
cbiACobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (464 aa)    
Predicted Functional Partners:
Paes_1290
TIGRFAM: precorrin-3B C17-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Precorrin-8X methylmutase CbiC/CobH; KEGG: cte:CT0387 precorrin-3B C17-methyltransferase/precorrin-8X methylmutase.
 
 0.962
Paes_1268
TIGRFAM: L-threonine-O-3-phosphate decarboxylase; PFAM: aminotransferase class I and II; KEGG: cph:Cpha266_1118 L-threonine O-3-phosphate decarboxylase.
  
 0.955
Paes_1288
KEGG: cte:CT0385 precorrin-4 C11-methyltransferase/cobalamin biosynthesis protein; TIGRFAM: precorrin-4 C11-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; cobalamin (vitamin B12) biosynthesis CbiG protein.
 
  
 0.953
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.946
Paes_1279
Cobaltochelatase; PFAM: CobN/magnesium chelatase; KEGG: cte:CT0418 cobalamin biosynthesis protein CobN.
 
 
 0.931
Paes_1275
Cobaltochelatase; PFAM: CobN/magnesium chelatase; KEGG: cte:CT0422 CobN protein, putative.
 
 
 0.930
cbiA-2
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
  
  
 
0.920
Paes_0326
TIGRFAM: ATP/cobalamin adenosyltransferase; PFAM: cobalamin adenosyltransferase; KEGG: pdi:BDI_1239 putative ATP:cob(I)alamin adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family.
    
 0.911
Paes_1289
KEGG: cte:CT0386 precorrin-6y C5,15-methyltransferase, decarboxylating; TIGRFAM: precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit; precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.884
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.844
Your Current Organism:
Prosthecochloris aestuarii
NCBI taxonomy Id: 290512
Other names: P. aestuarii DSM 271, Prosthecochloris aestuarii DSM 271, Prosthecochloris aestuarii SK 413, Prosthecochloris aestuarii SK413/DSMZ 271(t), Prosthecochloris aestuarii str. DSM 271, Prosthecochloris aestuarii strain DSM 271
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