node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Paes_0106 | Paes_1589 | Paes_0106 | Paes_1589 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | 0.742 |
Paes_0106 | guaB | Paes_0106 | Paes_1433 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.467 |
Paes_0106 | purD | Paes_0106 | Paes_0487 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | KEGG: cph:Cpha266_0528 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.477 |
Paes_0106 | purE | Paes_0106 | Paes_0597 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.540 |
Paes_1588 | Paes_1589 | Paes_1588 | Paes_1589 | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | 0.497 |
Paes_1588 | Paes_1590 | Paes_1588 | Paes_1590 | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: plt:Plut_1495 carbon-nitrogen hydrolase family protein. | 0.510 |
Paes_1588 | guaB | Paes_1588 | Paes_1433 | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.524 |
Paes_1589 | Paes_0106 | Paes_1589 | Paes_0106 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | 0.742 |
Paes_1589 | Paes_1588 | Paes_1589 | Paes_1588 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. | 0.497 |
Paes_1589 | Paes_1590 | Paes_1589 | Paes_1590 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: plt:Plut_1495 carbon-nitrogen hydrolase family protein. | 0.773 |
Paes_1589 | guaB | Paes_1589 | Paes_1433 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.509 |
Paes_1589 | purC | Paes_1589 | Paes_1375 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | KEGG: cph:Cpha266_1019 phosphoribosylaminoimidazole-succinocarboxamide synthase; TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase. | 0.515 |
Paes_1589 | purD | Paes_1589 | Paes_0487 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | KEGG: cph:Cpha266_0528 phosphoribosylamine--glycine ligase; TIGRFAM: phosphoribosylamine/glycine ligase; PFAM: phosphoribosylglycinamide synthetase; protein of unknown function DUF201; Belongs to the GARS family. | 0.532 |
Paes_1589 | purE | Paes_1589 | Paes_0597 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | Phosphoribosylaminoimidazole carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.524 |
Paes_1589 | purH | Paes_1589 | Paes_1700 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | KEGG: cph:Cpha266_0657 IMP cyclohydrolase / phosphoribosylaminoimidazolecarboxamide formyltransferase; TIGRFAM: phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM: MGS domain protein; AICARFT/IMPCHase bienzyme formylation region. | 0.506 |
Paes_1589 | purL | Paes_1589 | Paes_0996 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.517 |
Paes_1589 | purQ | Paes_1589 | Paes_1473 | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.497 |
Paes_1590 | Paes_1588 | Paes_1590 | Paes_1588 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: plt:Plut_1495 carbon-nitrogen hydrolase family protein. | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: cph:Cpha266_1878 alkyl hydroperoxide reductase/thiol specific antioxidant/Mal allergen. | 0.510 |
Paes_1590 | Paes_1589 | Paes_1590 | Paes_1589 | PFAM: Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase; KEGG: plt:Plut_1495 carbon-nitrogen hydrolase family protein. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: cph:Cpha266_1882 xanthine/uracil/vitamin C permease. | 0.773 |
guaB | Paes_0106 | Paes_1433 | Paes_0106 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | PFAM: Xanthine/uracil/vitamin C permease; KEGG: pth:PTH_2271 xanthine/uracil permeases. | 0.467 |