STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOX1232Gluconate 2-dehydrogenase gamma chain. (236 aa)    
Predicted Functional Partners:
GOX1231
Gluconate 2-dehydrogenase alpha chain.
 
 0.998
GOX1230
Gluconate 2-dehydrogenase, cytochrome c subunit.
 
  
 0.953
GOX0417
Putative 2-hydroxyacid dehydrogenase; Catalyzes the reduction of 2-keto-D-gluconate to gluconate. Can also catalyze the reduction of 2-keto-L-gulonate. Can use both NADH and NADPH efficiently, with a slight preference for NADPH. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
  
  0.911
GOX1375
Gluconolactonase.
     
 0.904
GOX1381
Gluconolactonase.
     
 0.904
GOX1709
Gluconokinase; Phosphorylates gluconate to 6-phosphogluconate. Belongs to the gluconokinase GntK/GntV family.
     
  0.900
adhB
Alcohol dehydrogenase cytochrome c subunit precursor; Cytochrome c component of the alcohol dehydrogenase multicomponent enzyme system which is involved in the production of acetic acid and in the ethanol oxidase respiratory chain. Quinohemoprotein alcohol dehydrogenase (ADH) catalyzes the oxidation of ethanol to acetaldehyde by transferring electrons to the ubiquinone embedded in the membrane phospholipids. The electrons transfer from ethanol to membranous ubiquinone occurs from pyrroloquinoline quinone (PQQ) to one heme c in subunit I (AdhA), and finally to two heme c in subunit II ( [...]
 
  
 0.852
GOX2095
Sorbitol dehydrogenase large subunit; Protein contains authentic frameshift.
 
 
 0.849
GOX2096
Sorbitol dehydrogenase large subunit; Protein contains authentic frameshift.
 
 
 0.841
GOX2094
Sorbitol dehydrogenase cytochrome c subunit.
 
  
 0.741
Your Current Organism:
Gluconobacter oxydans
NCBI taxonomy Id: 290633
Other names: G. oxydans 621H, Gluconobacter oxydans 621H, Gluconobacter oxydans str. 621H, Gluconobacter oxydans strain 621H
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.