| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| GOX0772 | tatA | GOX0772 | GOX1241 | Transcriptional regulator. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.643 |
| GOX1239 | GOX1245 | GOX1239 | GOX1245 | Hypothetical protein. | Riboflavin kinase; Belongs to the ribF family. | 0.620 |
| GOX1239 | mtnB | GOX1239 | GOX1242 | Hypothetical protein. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.570 |
| GOX1239 | mtnC | GOX1239 | GOX1244 | Hypothetical protein. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.562 |
| GOX1239 | mtnD | GOX1239 | GOX1243 | Hypothetical protein. | Putative dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.570 |
| GOX1239 | tatA | GOX1239 | GOX1241 | Hypothetical protein. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.630 |
| GOX1239 | thrB | GOX1239 | GOX0178 | Hypothetical protein. | Homoserine kinase; Belongs to the pseudomonas-type ThrB family. | 0.446 |
| GOX1245 | GOX1239 | GOX1245 | GOX1239 | Riboflavin kinase; Belongs to the ribF family. | Hypothetical protein. | 0.620 |
| GOX1245 | mtnB | GOX1245 | GOX1242 | Riboflavin kinase; Belongs to the ribF family. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.765 |
| GOX1245 | mtnC | GOX1245 | GOX1244 | Riboflavin kinase; Belongs to the ribF family. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.774 |
| GOX1245 | mtnD | GOX1245 | GOX1243 | Riboflavin kinase; Belongs to the ribF family. | Putative dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.763 |
| GOX1245 | tatA | GOX1245 | GOX1241 | Riboflavin kinase; Belongs to the ribF family. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.771 |
| GOX1757 | guaA | GOX1757 | GOX1950 | Sec-independent protein translocase protein TatB. | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | 0.972 |
| GOX1757 | tatA | GOX1757 | GOX1241 | Sec-independent protein translocase protein TatB. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.986 |
| GOX1757 | tatC | GOX1757 | GOX1758 | Sec-independent protein translocase protein TatB. | Sec-independent protein translocase protein TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides. | 0.996 |
| guaA | GOX1757 | GOX1950 | GOX1757 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Sec-independent protein translocase protein TatB. | 0.972 |
| guaA | tatA | GOX1950 | GOX1241 | GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.972 |
| mtnB | GOX1239 | GOX1242 | GOX1239 | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Hypothetical protein. | 0.570 |
| mtnB | GOX1245 | GOX1242 | GOX1245 | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Riboflavin kinase; Belongs to the ribF family. | 0.765 |
| mtnB | mtnC | GOX1242 | GOX1244 | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.999 |