node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GOX1239 | GOX1240 | GOX1239 | GOX1240 | Hypothetical protein. | Hypothetical protein. | 0.817 |
GOX1239 | GOX1245 | GOX1239 | GOX1245 | Hypothetical protein. | Riboflavin kinase; Belongs to the ribF family. | 0.620 |
GOX1239 | mtnB | GOX1239 | GOX1242 | Hypothetical protein. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.570 |
GOX1239 | mtnC | GOX1239 | GOX1244 | Hypothetical protein. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.562 |
GOX1239 | mtnD | GOX1239 | GOX1243 | Hypothetical protein. | Putative dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.570 |
GOX1239 | tatA | GOX1239 | GOX1241 | Hypothetical protein. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.630 |
GOX1240 | GOX1239 | GOX1240 | GOX1239 | Hypothetical protein. | Hypothetical protein. | 0.817 |
GOX1240 | GOX1245 | GOX1240 | GOX1245 | Hypothetical protein. | Riboflavin kinase; Belongs to the ribF family. | 0.564 |
GOX1240 | mtnB | GOX1240 | GOX1242 | Hypothetical protein. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.570 |
GOX1240 | mtnC | GOX1240 | GOX1244 | Hypothetical protein. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.562 |
GOX1240 | mtnD | GOX1240 | GOX1243 | Hypothetical protein. | Putative dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.570 |
GOX1240 | tatA | GOX1240 | GOX1241 | Hypothetical protein. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.571 |
GOX1245 | GOX1239 | GOX1245 | GOX1239 | Riboflavin kinase; Belongs to the ribF family. | Hypothetical protein. | 0.620 |
GOX1245 | GOX1240 | GOX1245 | GOX1240 | Riboflavin kinase; Belongs to the ribF family. | Hypothetical protein. | 0.564 |
GOX1245 | mtnB | GOX1245 | GOX1242 | Riboflavin kinase; Belongs to the ribF family. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.765 |
GOX1245 | mtnC | GOX1245 | GOX1244 | Riboflavin kinase; Belongs to the ribF family. | Putative enolase-phosphatase; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene). Belongs to the HAD-like hydrolase superfamily. MasA/MtnC family. | 0.774 |
GOX1245 | mtnD | GOX1245 | GOX1243 | Riboflavin kinase; Belongs to the ribF family. | Putative dioxygenase; Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway. | 0.763 |
GOX1245 | tatA | GOX1245 | GOX1241 | Riboflavin kinase; Belongs to the ribF family. | Sec-independent protein translocase protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.771 |
GOX2074 | mtnA | GOX2074 | GOX1605 | 5-Methyltetrahydrofolate-S-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Translation initiation factor, aIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). | 0.766 |
GOX2074 | mtnB | GOX2074 | GOX1242 | 5-Methyltetrahydrofolate-S-homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Probable sugar aldolase; Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Belongs to the aldolase class II family. MtnB subfamily. | 0.557 |