STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOX2181Putative polyol dehydrogenase. (257 aa)    
Predicted Functional Partners:
GOX2182
Probable mannitol/sorbitol ABC transporter permease protein.
     
 0.728
GOX0950
Putative oxidoreductase.
 
 
 
 0.639
GOX2418
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.627
GOX1538
Putative oxidoreductase; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
  
     0.623
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
      
 0.617
GOX2183
Probable mannitol/sorbitol ABC transporter ATP-binding protein.
       0.576
GOX2184
Probable mannitol/sorbitol ABC transporter permease protein.
       0.576
GOX0675
Alkaline phosphatase.
   
 
 0.476
GOX2180
TonB-dependent receptor (disrupted by IS element).
  
    0.456
GOX2179
Transposase (IS12528).
       0.453
Your Current Organism:
Gluconobacter oxydans
NCBI taxonomy Id: 290633
Other names: G. oxydans 621H, Gluconobacter oxydans 621H, Gluconobacter oxydans str. 621H, Gluconobacter oxydans strain 621H
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