STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOX2188Gluconate permease. (448 aa)    
Predicted Functional Partners:
GOX1709
Gluconokinase; Phosphorylates gluconate to 6-phosphogluconate. Belongs to the gluconokinase GntK/GntV family.
 
  
 0.603
gno
Gluconate 5-dehydrogenase; Catalyzes the reversible NADP-dependent oxidation of gluconate to 5-ketogluconate. Is involved in the non-phosphorylative, ketogenic oxidation of glucose. Is almost inactive with NAD as cosubstrate. Displays high substrate specificity since D-Glucose, D- sorbitol, and D-mannitol are not oxidized by the enzyme, and 2- ketogluconate and L-sorbose are not reduced. Can accept D-fructose as a substrate, with a rate that is only 10% of the rate of 5-ketogluconate reduction.
  
  
 0.503
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
      
 0.441
GOX1705
6-Phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NAD to NADH.
  
  
 0.424
GOX2189
Transposase (class I).
       0.403
Your Current Organism:
Gluconobacter oxydans
NCBI taxonomy Id: 290633
Other names: G. oxydans 621H, Gluconobacter oxydans 621H, Gluconobacter oxydans str. 621H, Gluconobacter oxydans strain 621H
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