node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
GOX0882 | GOX1073 | GOX0882 | GOX1073 | 2-Oxoglutarate dehydrogenase E1 component. | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | 0.999 |
GOX0882 | GOX2290 | GOX0882 | GOX2290 | 2-Oxoglutarate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.997 |
GOX0882 | GOX2291 | GOX0882 | GOX2291 | 2-Oxoglutarate dehydrogenase E1 component. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.995 |
GOX0882 | GOX2292 | GOX0882 | GOX2292 | 2-Oxoglutarate dehydrogenase E1 component. | Dihydrolipoamide dehydrogenase. | 0.997 |
GOX0882 | gcvH | GOX0882 | GOX1096 | 2-Oxoglutarate dehydrogenase E1 component. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.774 |
GOX0882 | gcvP | GOX0882 | GOX1097 | 2-Oxoglutarate dehydrogenase E1 component. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.839 |
GOX0882 | glyA | GOX0882 | GOX2310 | 2-Oxoglutarate dehydrogenase E1 component. | Serine hydroxymethyl transferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.407 |
GOX0882 | pdhA | GOX0882 | GOX2289 | 2-Oxoglutarate dehydrogenase E1 component. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.863 |
GOX1073 | GOX0882 | GOX1073 | GOX0882 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | 2-Oxoglutarate dehydrogenase E1 component. | 0.999 |
GOX1073 | GOX2290 | GOX1073 | GOX2290 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.996 |
GOX1073 | GOX2292 | GOX1073 | GOX2292 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | Dihydrolipoamide dehydrogenase. | 0.997 |
GOX1073 | gcvH | GOX1073 | GOX1096 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.748 |
GOX1073 | gcvP | GOX1073 | GOX1097 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | Glycine dehydrogenase [decarboxylating]; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.514 |
GOX1073 | pdhA | GOX1073 | GOX2289 | Dihydrolipoamide succinyl transferase (E2) of 2-oxoglutarate dehydrogenase. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.973 |
GOX1081 | GOX2290 | GOX1081 | GOX2290 | Pyruvate decarboxylase. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.940 |
GOX1081 | GOX2291 | GOX1081 | GOX2291 | Pyruvate decarboxylase. | Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.935 |
GOX1081 | GOX2292 | GOX1081 | GOX2292 | Pyruvate decarboxylase. | Dihydrolipoamide dehydrogenase. | 0.917 |
GOX1081 | pdhA | GOX1081 | GOX2289 | Pyruvate decarboxylase. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.911 |
GOX1095 | GOX2292 | GOX1095 | GOX2292 | Aminomethyltransferase (Glycine cleavage system T protein). | Dihydrolipoamide dehydrogenase. | 0.931 |
GOX1095 | gcvH | GOX1095 | GOX1096 | Aminomethyltransferase (Glycine cleavage system T protein). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.991 |