STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
DCAF8LOW QUALITY PROTEIN: DDB1- and CUL4-associated factor 8. (573 aa)    
Predicted Functional Partners:
DDB1
DNA damage-binding protein 1.
    
 0.963
CUL4A
cullin-4A; Belongs to the cullin family.
   
 0.856
CUL4B
LOW QUALITY PROTEIN: cullin-4B; Belongs to the cullin family.
   
 0.840
DCAF11
DDB1- and CUL4-associated factor 11; May function as a substrate receptor for CUL4-DDB1 E3 ubiquitin-protein ligase complex; Belongs to the WD repeat LEC14B family.
    
 0.798
DCAF4
DDB1- and CUL4-associated factor 4 isoform X2.
     
 0.790
DCAF5
DDB1- and CUL4-associated factor 5 isoform X1.
   
 
0.751
RBX1
E3 ubiquitin-protein ligase RBX1.
    
 0.749
APCDD1L
Protein APCDD1-like.
      
 0.742
DDB2
LOW QUALITY PROTEIN: DNA damage-binding protein 2.
    
 0.741
DCAF6
DDB1- and CUL4-associated factor 6.
     
0.695
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.