STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SPINK8Serine protease inhibitor Kazal-type 8. (135 aa)    
Predicted Functional Partners:
CAMSAP2
LOW QUALITY PROTEIN: calmodulin-regulated spectrin-associated protein 2.
      
 0.727
USP43
LOW QUALITY PROTEIN: ubiquitin carboxyl-terminal hydrolase 43.
      
 0.641
ARAP2
arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 2 isoform X2.
      
 0.598
ADAMTS14
A disintegrin and metalloproteinase with thrombospondin motifs 14.
      
 0.598
FCGBP
LOW QUALITY PROTEIN: IgGFc-binding protein.
      
 0.522
KRT71
Keratin, type II cytoskeletal 71 isoform X2; Belongs to the intermediate filament family.
      
 0.518
KRT73
Keratin, type II cytoskeletal 73; Belongs to the intermediate filament family.
      
 0.518
CHN2
Chimaerin; GTPase-activating protein for p21-rac.
      
 0.517
CHN1
Chimaerin; GTPase-activating protein for p21-rac.
      
 0.517
BPIFA1
BPI fold-containing family A member 1.
      
 0.516
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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