STXBP1 protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

STXBP1

Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family. (580 aa)

Predicted Functional Partners:

STX1A

0.999

STX1B

0.999

VAMP2

0.997

APBA1

0.995

STX3

0.976

STX2

0.976

SNAP25

0.961

RIMS2

0.890

RIMS1

0.859

STX4

0.796

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	RIMS1	ENSUMAP00000029948	ENSUMAP00000016647	Amyloid beta A4 precursor protein-binding family A member 1.	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	0.468
APBA1	RIMS2	ENSUMAP00000029948	ENSUMAP00000027462	Amyloid beta A4 precursor protein-binding family A member 1.	Regulating synaptic membrane exocytosis protein 2 isoform X1.	0.801
APBA1	SNAP25	ENSUMAP00000029948	ENSUMAP00000010138	Amyloid beta A4 precursor protein-binding family A member 1.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.577
APBA1	STX1A	ENSUMAP00000029948	ENSUMAP00000019018	Amyloid beta A4 precursor protein-binding family A member 1.	syntaxin-1A; Belongs to the syntaxin family.	0.847
APBA1	STX1B	ENSUMAP00000029948	ENSUMAP00000019103	Amyloid beta A4 precursor protein-binding family A member 1.	syntaxin-1B; Belongs to the syntaxin family.	0.847
APBA1	STX2	ENSUMAP00000029948	ENSUMAP00000027690	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin-2 isoform X1; Belongs to the syntaxin family.	0.596
APBA1	STX3	ENSUMAP00000029948	ENSUMAP00000025798	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin-3 isoform X1; Belongs to the syntaxin family.	0.596
APBA1	STX4	ENSUMAP00000029948	ENSUMAP00000019115	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin-4; Belongs to the syntaxin family.	0.596
APBA1	STXBP1	ENSUMAP00000029948	ENSUMAP00000000950	Amyloid beta A4 precursor protein-binding family A member 1.	Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family.	0.995
APBA1	VAMP2	ENSUMAP00000029948	ENSUMAP00000023727	Amyloid beta A4 precursor protein-binding family A member 1.	Vesicle-associated membrane protein 2.	0.421
RIMS1	APBA1	ENSUMAP00000016647	ENSUMAP00000029948	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	Amyloid beta A4 precursor protein-binding family A member 1.	0.468
RIMS1	SNAP25	ENSUMAP00000016647	ENSUMAP00000010138	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.872
RIMS1	STX1A	ENSUMAP00000016647	ENSUMAP00000019018	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	syntaxin-1A; Belongs to the syntaxin family.	0.780
RIMS1	STX1B	ENSUMAP00000016647	ENSUMAP00000019103	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	syntaxin-1B; Belongs to the syntaxin family.	0.780
RIMS1	STXBP1	ENSUMAP00000016647	ENSUMAP00000000950	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	Syntaxin-binding protein 1 isoform X1; Belongs to the STXBP/unc-18/SEC1 family.	0.859
RIMS1	VAMP2	ENSUMAP00000016647	ENSUMAP00000023727	LOW QUALITY PROTEIN: regulating synaptic membrane exocytosis protein 1.	Vesicle-associated membrane protein 2.	0.457
RIMS2	APBA1	ENSUMAP00000027462	ENSUMAP00000029948	Regulating synaptic membrane exocytosis protein 2 isoform X1.	Amyloid beta A4 precursor protein-binding family A member 1.	0.801
RIMS2	SNAP25	ENSUMAP00000027462	ENSUMAP00000010138	Regulating synaptic membrane exocytosis protein 2 isoform X1.	Synaptosomal-associated protein; Belongs to the SNAP-25 family.	0.798
RIMS2	STX1A	ENSUMAP00000027462	ENSUMAP00000019018	Regulating synaptic membrane exocytosis protein 2 isoform X1.	syntaxin-1A; Belongs to the syntaxin family.	0.811
RIMS2	STX1B	ENSUMAP00000027462	ENSUMAP00000019103	Regulating synaptic membrane exocytosis protein 2 isoform X1.	syntaxin-1B; Belongs to the syntaxin family.	0.811