SGK2 protein (Ursus maritimus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

SGK2

Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (367 aa)

Predicted Functional Partners:

SGK3

0.977

PDPK1

0.973

FOXO1

0.957

FOXO3

0.957

FOXO4

0.957

MTOR

0.916

SGK1

0.906

PRKAR1B

0.860

NEDD4L

0.858

NEDD4

0.858

Your Current Organism:

Ursus maritimus

NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXO1	FOXO3	ENSUMAP00000026699	ENSUMAP00000027234	Forkhead box protein O1.	Forkhead box protein O3.	0.912
FOXO1	FOXO4	ENSUMAP00000026699	ENSUMAP00000030965	Forkhead box protein O1.	Forkhead box protein O4 isoform X1.	0.853
FOXO1	MTOR	ENSUMAP00000026699	ENSUMAP00000032412	Forkhead box protein O1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.614
FOXO1	PDPK1	ENSUMAP00000026699	ENSUMAP00000031700	Forkhead box protein O1.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.407
FOXO1	SGK1	ENSUMAP00000026699	ENSUMAP00000033868	Forkhead box protein O1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968
FOXO1	SGK2	ENSUMAP00000026699	ENSUMAP00000001121	Forkhead box protein O1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.957
FOXO1	SGK3	ENSUMAP00000026699	ENSUMAP00000019559	Forkhead box protein O1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.935
FOXO3	FOXO1	ENSUMAP00000027234	ENSUMAP00000026699	Forkhead box protein O3.	Forkhead box protein O1.	0.912
FOXO3	FOXO4	ENSUMAP00000027234	ENSUMAP00000030965	Forkhead box protein O3.	Forkhead box protein O4 isoform X1.	0.872
FOXO3	MTOR	ENSUMAP00000027234	ENSUMAP00000032412	Forkhead box protein O3.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.457
FOXO3	PDPK1	ENSUMAP00000027234	ENSUMAP00000031700	Forkhead box protein O3.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.430
FOXO3	SGK1	ENSUMAP00000027234	ENSUMAP00000033868	Forkhead box protein O3.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.957
FOXO3	SGK2	ENSUMAP00000027234	ENSUMAP00000001121	Forkhead box protein O3.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.957
FOXO3	SGK3	ENSUMAP00000027234	ENSUMAP00000019559	Forkhead box protein O3.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.935
FOXO4	FOXO1	ENSUMAP00000030965	ENSUMAP00000026699	Forkhead box protein O4 isoform X1.	Forkhead box protein O1.	0.853
FOXO4	FOXO3	ENSUMAP00000030965	ENSUMAP00000027234	Forkhead box protein O4 isoform X1.	Forkhead box protein O3.	0.872
FOXO4	MTOR	ENSUMAP00000030965	ENSUMAP00000032412	Forkhead box protein O4 isoform X1.	Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family.	0.558
FOXO4	PDPK1	ENSUMAP00000030965	ENSUMAP00000031700	Forkhead box protein O4 isoform X1.	3-phosphoinositide-dependent protein kinase 1 isoform X1.	0.404
FOXO4	SGK1	ENSUMAP00000030965	ENSUMAP00000033868	Forkhead box protein O4 isoform X1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.968
FOXO4	SGK2	ENSUMAP00000030965	ENSUMAP00000001121	Forkhead box protein O4 isoform X1.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.957