node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AMFR | DERL1 | ENSUMAP00000001597 | ENSUMAP00000030370 | E3 ubiquitin-protein ligase AMFR. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.996 |
AMFR | DERL2 | ENSUMAP00000001597 | ENSUMAP00000018008 | E3 ubiquitin-protein ligase AMFR. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.949 |
AMFR | NGLY1 | ENSUMAP00000001597 | ENSUMAP00000026879 | E3 ubiquitin-protein ligase AMFR. | peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase. | 0.948 |
AMFR | OS9 | ENSUMAP00000001597 | ENSUMAP00000027657 | E3 ubiquitin-protein ligase AMFR. | Protein OS-9. | 0.930 |
AMFR | RAD23B | ENSUMAP00000001597 | ENSUMAP00000019362 | E3 ubiquitin-protein ligase AMFR. | LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B. | 0.882 |
AMFR | RPS27A | ENSUMAP00000001597 | ENSUMAP00000023029 | E3 ubiquitin-protein ligase AMFR. | ubiquitin-40S ribosomal protein S27a. | 0.889 |
AMFR | SEL1L | ENSUMAP00000001597 | ENSUMAP00000008923 | E3 ubiquitin-protein ligase AMFR. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.920 |
AMFR | UBE2G2 | ENSUMAP00000001597 | ENSUMAP00000035360 | E3 ubiquitin-protein ligase AMFR. | Ubiquitin-conjugating enzyme E2 G2 isoform X2; Belongs to the ubiquitin-conjugating enzyme family. | 0.955 |
AMFR | UBXN1 | ENSUMAP00000001597 | ENSUMAP00000019735 | E3 ubiquitin-protein ligase AMFR. | UBX domain-containing protein 1 isoform X1. | 0.947 |
AMFR | VCP | ENSUMAP00000001597 | ENSUMAP00000008374 | E3 ubiquitin-protein ligase AMFR. | Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. | 0.958 |
DERL1 | AMFR | ENSUMAP00000030370 | ENSUMAP00000001597 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | E3 ubiquitin-protein ligase AMFR. | 0.996 |
DERL1 | DERL2 | ENSUMAP00000030370 | ENSUMAP00000018008 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | 0.985 |
DERL1 | NGLY1 | ENSUMAP00000030370 | ENSUMAP00000026879 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | peptide-N(4)-(N-acetyl-beta- glucosaminyl)asparagine amidase. | 0.940 |
DERL1 | OS9 | ENSUMAP00000030370 | ENSUMAP00000027657 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Protein OS-9. | 0.961 |
DERL1 | RAD23B | ENSUMAP00000030370 | ENSUMAP00000019362 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | LOW QUALITY PROTEIN: UV excision repair protein RAD23 homolog B. | 0.868 |
DERL1 | RPS27A | ENSUMAP00000030370 | ENSUMAP00000023029 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | ubiquitin-40S ribosomal protein S27a. | 0.554 |
DERL1 | SEL1L | ENSUMAP00000030370 | ENSUMAP00000008923 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. | 0.975 |
DERL1 | UBE2G2 | ENSUMAP00000030370 | ENSUMAP00000035360 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Ubiquitin-conjugating enzyme E2 G2 isoform X2; Belongs to the ubiquitin-conjugating enzyme family. | 0.753 |
DERL1 | UBXN1 | ENSUMAP00000030370 | ENSUMAP00000019735 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | UBX domain-containing protein 1 isoform X1. | 0.967 |
DERL1 | VCP | ENSUMAP00000030370 | ENSUMAP00000008374 | Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family. | Transitional endoplasmic reticulum ATPase; Belongs to the AAA ATPase family. | 0.983 |