STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ROBO4LOW QUALITY PROTEIN: roundabout homolog 4. (981 aa)    
Predicted Functional Partners:
SLIT2
Slit homolog 2 protein isoform X1.
   
 0.920
SLIT1
LOW QUALITY PROTEIN: slit homolog 1 protein.
   
 0.843
SLIT3
Slit homolog 3 protein.
   
 0.786
UNC5B
Netrin receptor UNC5B.
     
0.779
GIT1
ARF GTPase-activating protein GIT1.
      
 0.769
PXN
Paxillin.
      
 0.760
EMCN
Endomucin.
   
  
 0.673
LRTM2
Leucine-rich repeat and transmembrane domain-containing protein 2.
   
 0.672
MMRN2
Multimerin 2.
   
 
 0.670
DLL4
Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.
   
  
 0.628
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.