STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCGF1Polycomb group RING finger protein 1 isoform X3. (363 aa)    
Predicted Functional Partners:
RING1
E3 ubiquitin-protein ligase RING1.
   
0.993
RNF2
E3 ubiquitin-protein ligase RING2 isoform X1.
   
 0.992
CBX8
Chromobox protein homolog 8.
    
 0.977
PCGF5
Polycomb group RING finger protein 5 isoform X3.
    
0.975
RYBP
RING1 and YY1-binding protein.
    
 0.973
KDM2B
LOW QUALITY PROTEIN: lysine-specific demethylase 2B.
   
 0.972
BMI1
Polycomb complex protein BMI-1.
    
0.969
CBX7
Chromobox protein homolog 7.
    
 0.966
PCGF3
Polycomb group RING finger protein 3 isoform X1.
    
0.950
YAF2
YY1-associated factor 2.
    
 0.947
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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