STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LRSAM1E3 ubiquitin-protein ligase LRSAM1. (685 aa)    
Predicted Functional Partners:
CALCOCO2
Calcium-binding and coiled-coil domain-containing protein 2.
    
 0.789
STK25
Serine/threonine-protein kinase 25.
   
 
 0.779
STK26
Serine/threonine-protein kinase MST4.
   
 
 0.775
STK24
Serine/threonine-protein kinase 24 isoform X1.
   
 
 0.775
RNF166
RING finger protein 166.
    
 
 0.766
TSG101
Tumor susceptibility gene 101 protein.
    
 
 0.714
ADGRL1
Latrophilin-1; Belongs to the G-protein coupled receptor 2 family.
    
   0.692
ADGRL2
Latrophilin-2; Belongs to the G-protein coupled receptor 2 family.
    
   0.692
ADGRL3
Latrophilin-3; Belongs to the G-protein coupled receptor 2 family.
    
   0.692
TRIM21
E3 ubiquitin-protein ligase TRIM21.
    
 
 0.647
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.