STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GNASGuanine nucleotide-binding protein G(S) subunit alpha isoform X1. (672 aa)    
Predicted Functional Partners:
ADCY9
Adenylate cyclase type 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.
    
 0.993
GNB4
Guanine nucleotide-binding protein subunit beta-4 isoform X1.
   
 0.986
ADCY2
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.979
ADCY5
Adenylate cyclase; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
   
 0.979
ADRB2
Beta-2 adrenergic receptor.
    
 0.977
ADGRD1
Probable G-protein coupled receptor 133; Belongs to the G-protein coupled receptor 2 family.
    
 
 0.970
GNG2
Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction.
   
 0.949
GLP1R
Glucagon-like peptide 1 receptor; Belongs to the G-protein coupled receptor 2 family.
    
 0.758
GNB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2.
   
 0.740
GNB5
Guanine nucleotide-binding protein subunit beta-5.
   
 0.701
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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