STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BRD4Bromodomain-containing protein 4 isoform X2. (1264 aa)    
Predicted Functional Partners:
E2F1
Transcription factor E2F1.
    
 
 0.990
NSD3
Histone-lysine N-methyltransferase NSD3 isoform X2.
   
 
 0.966
CDK9
Cyclin-dependent kinase 9.
   
 
 0.960
JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6.
    
 
 0.959
CCNT1
cyclin-T1 isoform X1; Belongs to the cyclin family.
   
 
 0.938
RELA
Transcription factor p65.
   
 
 0.908
CRBN
Protein cereblon.
    
 
 0.876
H3F3B
H3 histone, family 3B.
   
 
 0.819
H3F3A
H3 histone, family 3A.
   
 
 0.819
EP300
LOW QUALITY PROTEIN: histone acetyltransferase p300.
   
0.817
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.