STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NOSIPNitric oxide synthase-interacting protein; Negatively regulates nitric oxide production by inducing NOS1 and NOS3 translocation to actin cytoskeleton and inhibiting their enzymatic activity; Belongs to the NOSIP family. (62 aa)    
Predicted Functional Partners:
NOS3
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.888
RCN3
LOW QUALITY PROTEIN: reticulocalbin-3.
      
 0.754
LCMT1
Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family.
      
 0.636
NOS1
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.566
NOS2
Nitric oxide synthase; Produces nitric oxide (NO).
    
 0.566
TRAPPC2L
Trafficking protein particle complex subunit 2-like protein isoform X3.
      
 0.527
ARHGEF19
Rho guanine nucleotide exchange factor 19.
      
 0.525
XPNPEP2
xaa-Pro aminopeptidase 2; Belongs to the peptidase M24B family.
      
 0.518
SFXN4
Sideroflexin-4.
      
 0.517
FDX1
Adrenodoxin, mitochondrial.
      
 0.515
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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