STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BICD1Protein bicaudal D homolog 1 isoform X1. (835 aa)    
Predicted Functional Partners:
DCTN2
Dynactin subunit 2 isoform X2.
    
 0.889
DCTN1
Dynactin subunit 1 isoform X1.
    
 0.875
DYNC1LI1
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.872
BICD2
Protein bicaudal D homolog 2.
  
 
0.837
RAB6A
LOW QUALITY PROTEIN: ras-related protein Rab-6A.
    
 0.812
RAB6B
Ras-related protein Rab-6B.
    
 0.812
DYNC1LI2
Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes.
    
 0.775
DYNC1I1
Cytoplasmic dynein 1 intermediate chain 1 isoform X2.
    
  0.735
DYNC1H1-2
Dynein cytoplasmic 1 heavy chain 1.
    
 0.710
DYNC1H1
LOW QUALITY PROTEIN: cytoplasmic dynein 1 heavy chain 1.
    
 0.710
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.