STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GOPCGolgi-associated PDZ and coiled-coil motif-containing protein. (433 aa)    
Predicted Functional Partners:
CFTR
Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer.
   
 0.898
PICK1
PRKCA-binding protein.
   
 0.818
TTC26
Tetratricopeptide repeat protein 26 isoform X1.
   
 0.780
DPY19L2
Probable C-mannosyltransferase DPY19L2.
   
  
 0.761
CCDC62
Coiled-coil domain-containing protein 62 isoform X3.
      
 0.753
SPATA16
LOW QUALITY PROTEIN: spermatogenesis-associated protein 16.
      
 0.729
STOML1
Stomatin-like protein 1 isoform X3.
   
  
 0.711
RHOQ
Rho-related GTP-binding protein RhoQ.
    
 0.699
KIFAP3
Kinesin-associated protein 3.
    
 0.660
LOC103672496
Membrane cofactor protein-like isoform X1.
    
 
 0.638
Your Current Organism:
Ursus maritimus
NCBI taxonomy Id: 29073
Other names: Thalarctos maritimus, U. maritimus, polar bear, white bear
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.